Causes of Myasthenia Gravis

dedicated to raising awareness of Myasthenia Gravis.

Today, let’s learn causes of MG
and what can cause MG to get worse

So we have learned the name myasthenia gravis, how to say it, common symptoms, related terms, learned some myths, how MG feels, who might get MG, and what a crisis is. Now, let’s learn causes.


The National Organization for Rare Diseases (NORD) website states amid their extensive section on causes: Myasthenia gravis is caused by an abnormal immune reaction (antibody-mediated autoimmune response) in which the body’s immune defenses (i.e., antibodies) inappropriately attack certain proteins in muscles that receive nerve impulses.

The NORD site also indicates: “…the disorder [MG] appears to occur spontaneously (sporadically) for unknown reasons.”

A cause of MG is complex, and requires the evaluation of a professional health care specialist. If myasthenia gravis has begun to ring a bell as a possible disorder for discussion with your doctor, these links to sites that give far more discussion about ’causes’ might add to your convictions, either way. They are a places to begin.

Causes/Inheritance – MDA
Myasthenia Gravis causes – MGN
What causes MG? –Conquer MG
What causes myasthenia gravis? – NIH


The Muscular Dystrophy Association website relates that “although MG and other autoimmune diseases are not hereditary, genetic susceptibility does appear to play a role. It seems likely that genetic factors also contribute to the pathogenesis of MG.”

“The U.S. National Library of Medicine website relates: “In most cases, myasthenia gravis is not inherited and occurs in people with no history of the disorder in their family. About 3 to 5 percent of affected individuals have other family members with myasthenia gravis or other autoimmune disorders, but the inheritance pattern is unknown.”

Myasthenia gravis is inconsistent, called the ‘snowflake disease,’ different with each person, not to mention the overlap in symptoms with other diseases, making it hard to diagnose. Keep checking with the numerous websites to add to your knowledge.

And then sometimes I even forget I have MG until the symptoms raise their head and I remember, “ooh, yes, I have trouble walking. What triggered that?”

What can cause MG to get worse?

There are instances where triggers make MG worse. It is worth researching more than what is here because not all instances relate to every case of MG. Keep your list of what relates to you! Let your doctor know.

  • We know fatigue makes our muscles weaker, but lack of sleep apparently can add to the fatigue as well.
  • As with many illness, stress is named as a trigger for MG fatigue.
  • Humidity has been a serious trigger for me and is on the list of what to monitor.
  • Bright sunlight and extreme temperatures; hot, with humidity, saunas, sunbathing, hot baths or hot showers or hot tubs, or cold.
  • One thing that still triggers drooping eyelids for me is flashing of strobe lights. It is worse with mullti-colored lights, used with a disco ball with mirrors.
  • Exposure to any number of chemicals for lawns, housekeeping or insect sprays. Note which ones and talk to your doctor.
  • Pain and illness can bring on fatigue.

Want to walk for,
or donate Canada to,
Myasthenia Gravis Society of Canada?
Visit Step Up for MG Fit or Press Release

** This site is not associated with the MG groups mentioned on this site. We just know MG research cannot go forward without donations/funding.

Watch our right side bar to see most recent posts about many aspects of Myasthenia Gravis.

Having these symptoms does not mean you have MG, but they might be an indicator for discussion with your doctor about symptoms.

I am so glad you have become part of the raising awareness campaign. As we learn more we are able to tell others.

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others can learn by reading what you have discovered… a site solely for awareness of Myasthenia Gravis.

Six days – causes of MG © 2021 Judith Allen Shone

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